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David, Sean
One or more keywords matched the following properties of David, Sean
PropertyValue
keywords Public Health
overview I am a clinical and translational physician scientist with interests in alcohol and nicotine genomic discovery science, pharmacogenomics, precision medicine, tobacco cessation, implementation science, community-engaged research, and health equity. I am the NorthShore Site Leader for the Institute for Translational Medicine, Program Director for Translational Science for the Outcomes Research Network, and I am Vice Chair for Research for the Department of Family Medicine.
One or more keywords matched the following items that are connected to David, Sean
Item TypeName
Concept Attitude of Health Personnel
Concept Chromosomes, Human, Pair 15
Concept Health Surveys
Concept Delivery of Health Care
Concept Chromosomes, Human, Pair 10
Concept Community Health Services
Concept Marketing of Health Services
Concept Primary Health Care
Concept Health Policy
Concept Patient Acceptance of Health Care
Concept Health Knowledge, Attitudes, Practice
Concept Humans
Concept United States
Concept Women's Health
Concept Mental Health
Concept Health Care Reform
Concept Community Health Planning
Concept Delivery of Health Care, Integrated
Concept Public Health Administration
Concept Genome, Human
Concept Health Care Surveys
Concept Chromosomes, Human, X
Academic Article Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25.
Academic Article Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium.
Academic Article Implementing Primary Care Mediated Population Genetic Screening Within an Integrated Health System.
Academic Article Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices.
Academic Article The mental health burden of racial and ethnic minorities during the COVID-19 pandemic.
Academic Article Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing.
Academic Article Genetic diversity fuels gene discovery for tobacco and alcohol use.
Academic Article Cross-sectional online survey of clinicians' knowledge, attitudes and challenges to screening and counselling adolescents and young adults for substance use.
Academic Article Symptom prevalence, duration, and risk of hospital admission in individuals infected with SARS-CoV-2 during periods of omicron and delta variant dominance: a prospective observational study from the ZOE COVID Study.
Academic Article A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response.
Academic Article Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program.
Academic Article Genome sequencing unveils a regulatory landscape of platelet reactivity.
Academic Article Target specific serologic analysis of COVID-19 convalescent plasma.
Academic Article The association between cigarette smoking, cancer screening, and cancer stage: a prospective study of the women's health initiative observational cohort.
Academic Article Perspectives on Precision Health Among Racial/Ethnic Minority Communities and the Physicians That Serve Them.
Academic Article De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.
Academic Article Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma.
Academic Article Smoking Cessation Pharmacotherapy Based on Genetically-Informed Biomarkers: What is the Evidence?
Academic Article Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci.
Academic Article Deep-coverage whole genome sequences and blood lipids among 16,324 individuals.
Academic Article Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.
Academic Article Potential Reporting Bias in Neuroimaging Studies of Sex Differences.
Academic Article Whole genome sequence analyses of brain imaging measures in the Framingham Study.
Academic Article Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers.
Academic Article Leveraging Genomic Data in Smoking Cessation Trials in the Era of Precision Medicine: Why and How.
Academic Article The Value of Biosamples in Smoking Cessation Trials: A Review of Genetic, Metabolomic, and Epigenetic Findings.
Academic Article Extended treatment for cigarette smoking cessation: a randomized control trial.
Academic Article Persistent alterations of gene expression profiling of human peripheral blood mononuclear cells from smokers.
Academic Article Medical school curriculum characteristics associated with intentions and frequency of tobacco dependence treatment among 3rd year U.S. medical students.
Academic Article Smoking behavior and association of melanoma and nonmelanoma skin cancer in the Women's Health Initiative.
Academic Article Effects of nicotine deprivation and replacement on BOLD-fMRI response to smoking cues as a function of DRD4 VNTR genotype.
Academic Article A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies.
Academic Article Whole genome sequence analysis of blood lipid levels in >66,000 individuals.
Academic Article Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals.
Academic Article Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data.
Academic Article Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers.
Academic Article Whole Genome Sequence Analysis of the Plasma Proteome in Black Adults Provides Novel Insights Into Cardiovascular Disease.
Academic Article Variant-specific inflation factors for assessing population stratification at the phenotypic variance level.
Academic Article Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.
Academic Article Whom Should We Test for COVID-19? Performance of a Symptom and Risk Factor Questionnaire on COVID-19 Test Results and Patient Outcomes in an Immediate Care Setting.
Academic Article Effect of Sickle Cell Trait and APOL1 Genotype on the Association of Soluble uPAR with Kidney Function Measures in Black Americans.
Academic Article Inherited causes of clonal haematopoiesis in 97,691 whole genomes.
Academic Article Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale.
Academic Article Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use.
Academic Article Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.
Academic Article From genes to treatments: a systematic review of the pharmacogenetics in smoking cessation.
Academic Article Clinical and Personal Utility of Genetic Risk Testing.
Academic Article Retrospective analysis of changing characteristics of treatment-seeking smokers: implications for further reducing smoking prevalence.
Academic Article Gene by Environment Investigation of Incident Lung Cancer Risk in African-Americans.
Academic Article Gene by Environment Interaction Linking the Chromosome 15q25 Locus with Cigarette Consumption and Lung Cancer Susceptibility--Are African American Affected Differently?--Authors' Reply.
Academic Article Teaching Medical Students to Help Patients Quit Smoking: Outcomes of a 10-School Randomized Controlled Trial.
Academic Article Making Personalized Health Care Even More Personalized: Insights From Activities of the IOM Genomics Roundtable.
Academic Article Differential Efficacy of Nicotine Replacement Among Overweight and Obese Women Smokers.
Academic Article Association of CHRNA5-A3-B4 SNP rs2036527 with smoking cessation therapy response in African-American smokers.
Academic Article Publication and other reporting biases in cognitive sciences: detection, prevalence, and prevention.
Academic Article Systematic review and meta-analysis of opioid antagonists for smoking cessation.
Academic Article Commentary on Chen et?al. (2014): another step on the road to clinical utility of pharmacogenetics for smoking cessation?
Academic Article No association between germline variation in catechol-O-methyltransferase and colorectal cancer survival in postmenopausal women.
Academic Article Biomarkers for smoking cessation.
Academic Article Pharmacogenetic smoking cessation intervention in a health care setting: a pilot feasibility study.
Academic Article The neuroeconomics of nicotine dependence: a preliminary functional magnetic resonance imaging study of delay discounting of monetary and cigarette rewards in smokers.
Academic Article Association between daily cigarette consumption and hypertension moderated by CYP2A6 genotypes in Chinese male current smokers.
Academic Article Phased whole-genome genetic risk in a family quartet using a major allele reference sequence.
Academic Article Use of prechemotherapy positron emission tomography-CT imaging, acquired in the treatment position, to help plan involved nodal radiotherapy for a patient with diffuse large B-cell lymphoma.
Academic Article Dopamine D4 receptor gene variation moderates the efficacy of bupropion for smoking cessation.
Academic Article Sex differences in TTC12/ANKK1 haplotype associations with daily tobacco smoking in Black and White Americans.
Academic Article Association of the DRD2 gene Taq1A polymorphism and smoking behavior: a meta-analysis and new data.
Academic Article [Smoking cessation].
Academic Article Genetic variation in the serotonin pathway and smoking cessation with nicotine replacement therapy: new data from the Patch in Practice trial and pooled analyses.
Academic Article Smoking cessation.
Academic Article Pharmacogenetic clinical trial of sustained-release bupropion for smoking cessation.
Academic Article Successful Latino community partnership program for smoking cessation.
Academic Article The serotonin transporter 5-HTTLPR polymorphism and treatment response to nicotine patch: follow-up of a randomized controlled trial.
Academic Article Building a successful research enterprise in family medicine: the Brown experience.
Academic Article Tobacco dependence treatment teaching by medical school clerkship preceptors: survey responses from more than 1,000 US medical students.
Academic Article Should we use multiple risk factor interventions for the primary prevention of coronary heart disease?
Academic Article Are family physicians willing to use pharmacogenetics for smoking cessation therapy?
Academic Article Fellowship training in family medicine at Brown: adding depth to breadth.
Academic Article Genetic susceptibility to breast cancer: teaching points.
Academic Article Does the DRD2-Taq1 A polymorphism influence treatment response to bupropion hydrochloride for reduction of the nicotine withdrawal syndrome?
Academic Article Social marketing: application to medical education.
Academic Article Does providing hereditary breast cancer risk assessment support to practicing physicians decrease the likelihood of them discussing such risk with their patients?
Academic Article A functional genetic variation of the serotonin (5-HT) transporter affects 5-HT1A receptor binding in humans.
Academic Article Should we recommend nicotine replacement therapy?
Academic Article Teaching tobacco dependence treatment and counseling skills during medical school: rationale and design of the Medical Students helping patients Quit tobacco (MSQuit) group randomized controlled trial.
Academic Article Evidence of reporting biases in voxel-based morphometry (VBM) studies of psychiatric and neurological disorders.
Academic Article Influence of a dopamine pathway additive genetic efficacy score on smoking cessation: results from two randomized clinical trials of bupropion.
Academic Article Potential reporting bias in fMRI studies of the brain.
Academic Article Opioid antagonists for smoking cessation.
Academic Article Communities of solution: partnerships for population health.
Academic Article Genome-wide meta-analyses of smoking behaviors in African Americans.
Academic Article PharmGKB summary: very important pharmacogene information for cytochrome P-450, family 2, subfamily A, polypeptide 6.
Academic Article Chronic psychosocial stressors and salivary biomarkers in emerging adults.
Academic Article Relationship between amounts of daily cigarette consumption and abdominal obesity moderated by CYP2A6 genotypes in Chinese male current smokers.
Academic Article Association between CHRNA5 genetic variation at rs16969968 and brain reactivity to smoking images in nicotine dependent women.
Academic Article Pharmacogenetics of smoking cessation in general practice: results from the patch II and patch in practice trials.
Academic Article Associations of CYP2A6 genotype with smoking behaviors in southern China.
Academic Article Effects of nicotine withdrawal on verbal working memory and associated brain response.
Academic Article Genome-wide association for smoking cessation success: participants in the Patch in Practice trial of nicotine replacement.
Academic Article Smoking cessation in primary care.
Academic Article A cost-effectiveness analysis of genetic testing of the DRD2 Taq1A polymorphism to aid treatment choice for smoking cessation.
Academic Article Bupropion efficacy for smoking cessation is influenced by the DRD2 Taq1A polymorphism: analysis of pooled data from two clinical trials.
Academic Article Association of COMT Val108/158Met genotype with smoking cessation in a nicotine replacement therapy randomized trial.
Academic Article Genetic variation in the dopamine D4 receptor (DRD4) gene and smoking cessation: follow-up of a randomised clinical trial of transdermal nicotine patch.
Academic Article No association between functional catechol O-methyl transferase 1947A>G polymorphism and smoking initiation, persistent smoking or smoking cessation.
Academic Article Should we offer routine breast cancer screening with mammography?
Academic Article Comment on "The public health implications of smoking-induced decreased serum and red blood cell folate levels".
Academic Article Reflections from a rotation in Cambridge, England.
Academic Article Pharmacogenetics.
Academic Article Envisaging and applying a unifying three-dimensional theoretical framework for generalist physicians.
Academic Article Clinical interpretation and implications of whole-genome sequencing.
Academic Article Improving America's health requires community-level solutions: Folsom revisited.
Academic Article Communities of solution: the Folsom Report revisited.
Academic Article Interaction between heavy smoking and CYP2A6 genotypes on type 2 diabetes and its possible pathways.
Academic Article Genetic variation in the dopamine pathway and smoking cessation.
Academic Article Molecular genetics of successful smoking cessation: convergent genome-wide association study results.
Academic Article Chronic cigarette smoking and the microstructural integrity of white matter in healthy adults: a diffusion tensor imaging study.
Academic Article Should we prescribe antibiotics for acute conjunctivitis?
Academic Article Are there sex differences in transdermal nicotine replacement therapy patch efficacy? A meta-analysis.
Academic Article Ventral striatum/nucleus accumbens activation to smoking-related pictorial cues in smokers and nonsmokers: a functional magnetic resonance imaging study.
Concept Social Determinants of Health
Grant Exploratory/Developmental Study of Pharmacogenetic Smoking Cessation Therapy
Grant Primary Care Genetics Cancer Prevention Conference
Academic Article Do medications increase the efficacy of digital interventions for smoking cessation? Secondary results from the iCanQuit randomized trial.
Academic Article Personalized medicine in a community health system: the NorthShore experience.
Academic Article Effects of Social Determinants and Pharmacogenetic Medication Interactions on 90-Day Hospital Readmissions.
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